Effectiveness of siwak salvadora persica extract to aggregatibacter actinomycetemcomitans as one of pathogenic bacteria causing periodontal disease
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چکیده
منابع مشابه
Anthelmintic Activity of Salvadora Persica Root Extract against Pheretima Posthuma
Helminthes infections are the most common health problems in India, in developing countries they pose a large treat to public. These infections can affect most population in endemic areas with major economic and social consequences. The miswak is a natural toothbrush made from the twigs of the Salvadora persica (Salvadoraceae). Miswak prevents tooth decay, eliminating toothaches and halt furthe...
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Aggregatibacter actinomycetemcomitans is a Gram-negative periodontitis-associated bacterium that expresses a toxin that selectively affects leukocytes. This leukotoxin is encoded by an operon belonging to the core genome of this bacterial species. Variations in the expression of the leukotoxin have been reported, and a well-characterized specific clonal type (JP2) of this bacterium with enhance...
متن کاملRole of Exopolysaccharide in Aggregatibacter actinomycetemcomitans–Induced Bone Resorption in a Rat Model for Periodontal Disease
Aggregatibacter actinomycetemcomitans a causative agent of periodontal disease in humans, forms biofilm on biotic and abiotic surfaces. A. actinomycetemcomitans biofilm is heterogeneous in nature and is composed of proteins, extracellular DNA and exopolysaccharide. To explore the role played by the exopolysaccharide in the colonization and disease progression, we employed genetic reduction appr...
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Our aim was to explore the effects of Cytolethal Distending toxin (Cdt) in a well established rat model of periodontal disease where leukotoxin (LtxA) was thought to have no known effect. In vitro studies, were used to assess CdtB activity using Aa Leukotoxin as a negative control. These studies showed that both CdtB and LtxA (unexpectedly) exerted significant effects on CD4(+) T cells. As a re...
متن کاملEffects of Salvadora persica Extract on the Hematological and Biochemical Alterations against Immobilization-Induced Rats
A total of 24 rats were divided into 4 groups: control, stress, extract alone, and stress + extract (n = 6 each), for total 21 days of treatment. The immobilization stress was induced in rats by putting them in 20 cm × 7 cm plastic tubes for 2 h/day for 21 days. Rats were postorally treated with Salvadora persica at a dose of 900 mg/kg body weight via intragastric intubations. At the end of the...
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ژورنال
عنوان ژورنال: Journal of Dentomaxillofacial Science
سال: 2017
ISSN: 2503-0825,2503-0817
DOI: 10.15562/jdmfs.v2i1.449